Introduction. Menstrual bleeding cessation is one of the most frequent gynecologic disorders among women in reproductive\nage. The treatment is based on hormone therapy. Due to the increasing request for alternative medicine remedies in the field\nof women�s diseases, in present study, it was tried to overview medicinal plants used to treat oligomenorrhea and amenorrhea\naccording to the pharmaceutical textbooks of traditional Persian medicine (TPM) and review the evidence in the conventional\nmedicine. Methods. This systematic review was designed and performed in 2017 in order to gather information regarding herbal\nmedications of oligomenorrhea and amenorrhea in TPM and conventional medicine. This study had several steps as searching\nIranian traditional medicine literature and extracting the emmenagogue plants, classifying the plants, searching the electronic\ndatabases, and finding evidences. To search traditional Persian medicine references, Noor digital library was used, which includes\nseveral ancient traditional medical references. The classification of plants was done based on the repetition and potency of the\nplants in the ancient literatures.Therequired data was gathered using databases such as PubMed, Scopus,Google Scholar, Cochrane\nLibrary, Science Direct, and web of knowledge. Results. In present study of all 198 emmenagogue medicinal plants found in TPM, 87\ncaseswere specified to bemore effective in treating oligomenorrhea and amenorrhea. In second part of present study,where a search\nof conventional medicine was performed, 12 studies were found, which had 8 plants investigated: Vitex agnus-castus, Trigonella\nfoenum-graecum, Foeniculum vulgare, Cinnamomum verum, Paeonia lactiflora, Sesamum indicum, Mentha longifolia, and Urtica\ndioica. Conclusion. Traditional Persian medicine has proposed many different medicinal plants for treatment of oligomenorrhea\nand amenorrhea. Although just few plants have been proven to be effective for treatment of menstrual irregularities, the results and\nthe classification in present study can be used as an outline for future studies and treatment.
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